The endocannabinoid system (ECS) is a widespread neuromodulatory system. The existence of this system of cells explains why cannabis has so many medicinal and therapeutic effects. It plays important roles in central nervous system development, synaptic plasticity, and the response to endogenous and environmental insults. It’s a is a complex cell-signaling system identified in the early 1990s by researchers exploring THC. The ECS comprises a vast network of chemical signals and cellular receptors that are densely packed throughout our brains and bodies.